Hemorrhagic fever with renal syndrome etiology, and understanding its causes. The causative agent of hemorrhagic nephritis is nephroso-virus in the blood and urine of patients during the acute stage of illness. Epidemiology remains poorly understood, although in the middle zone of European part of the former Soviet Union established seasonality of the disease (2nd half of November and December), due to the migration of field rodents to housing man. It is known that sick people often living in river valleys, lakes, woodlands, a little populated and sparsely populated areas. The disease belongs to the category of diseases with natural foci, occurs in areas where a large number of rodents (various species of voles, particularly the eastern harvest mouse, rat, Carax).
Many authors have emphasized the role of ticks as a reservoir gamasid infection. Ways of transmission to humans not fully understood. Suggest that there has been contact, food, dust and methods of infection (through items, food, dust, contaminated secretions of rodents). The transmission mode of transmission (through mites) is not fully proven. From human to human infection is not transmitted.
Clinic. The incubation period-from 11 to 30 days (on average about 15 days). The disease often begins with chills and high fever. However, in some cases for 2-3 day to a high temperature can be observed prodromal phenomena, such as the slight malaise, low-grade fever, mild sore throat. Then the temperature rises to a fever from 38-40 , is held in high numbers in average of 4-5 days, and then Cruise analytically reduced to rule. In some patients, the temperature curve humped, others intermittent, and only in individual patients the disease runs in the background subfebrile temperature. In Depending on the symptoms of the disease distinguish 3 periods: the first – a general toxic, it takes 2-3 days of illness, the second period of hemorrhagic manifestations and renal failure, it starts with a 3-4th day of illness on the background Fever and fever-free period lasts, third – the recovery period.
